Between May and July 2025, our research team conducted a comprehensive study of the top healthcare lead generation agencies in the U.S. We evaluated 54 agencies, selecting the 7 highest-scoring firms to feature in the table below. Our comparison methodology was based on a weighted algorithm considering the following factors:
- Industry-Specific Expertise (25%)
- Average Client ROI (20%)
- Regulatory Compliance Knowledge (15%)
- Quality of Thought Leadership (15%)
- Leadership Experience Score (10%)
- Media References (10%)
- Specialty (5%)
We then rank-ordered the agencies based on these criteria, presenting them in the table below. Following the table, we provide an in-depth analysis of each firm, including a summary of online reviews.
The Top Healthcare Lead Generation Agencies of 2025
Rank | Company | Industry-Specific Expertise | Average Client ROI | Regulatory Compliance Knowledge | Thought Leadership | Leadership Experience Score | Media References | Specialty |
1 | First Page Sage | 5/5 | 32% | 5/5 | 5/5 | 4.9 | ~8010 | SEO-driven thought leadership |
2 | Rocket Healthcare Marketing | 4/5 | 24% | 4/5 | 4/5 | 4.6 | ~20 | Multichannel campaigns |
3 | Callbox | 4/5 | 22% | 4/5 | 4/5 | 4.4 | ~180 | B2B healthcare lead generation |
4 | Revnew | 3/5 | 21% | 3/5 | 3/5 | 4.3 | ~120 | Medical sales leads |
5 | Launch Leads | 3/5 | 20% | 4/5 | 3/5 | 4.1 | ~60 | Appointment setting |
6 | PointClear | 3/5 | 19% | 3/5 | 3/5 | 4.0 | ~90 | Prospect development |
7 | Zocdoc | 4/5 | 26% | 5/5 | 4/5 | 4.5 | ~1,700 | Patient appointment platform |
Agency Summaries
Below, we’ve delved a bit deeper into each agency and their offerings for healthcare organizations.
First Page Sage

First Page Sage has established itself as a powerhouse in healthcare lead generation by marrying deep industry expertise with long-form, trust-building content. Rather than chasing vanity metrics, the firm specializes in SEO strategies that steadily convert high-intent traffic into qualified leads. Its proprietary approach—rooted in educational content and domain authority—has proven especially effective for complex or high-ticket healthcare services. While results tend to build over quarters rather than weeks, the lead quality is among the highest in the category, making First Page Sage a favorite for organizations playing the long game.
Location: San Francisco, CA
Year Established: 2009
Price Range: $$$$
Average Review Score: 4.9/5
Services Offered: SEO, content marketing, analytics
Summary of Online Reviews |
Clients say they’re “surprised by the quality of leads”, calling their content “insightful and persuasive”; some note “strategic campaigns can take longer to ramp up” but praise the long-term results. |
Rocket Healthcare Marketing

Rocket Healthcare Marketing delivers on its name, offering fast-moving, multifaceted campaigns that cut across SEO, paid media, and CRM. Its creative department is particularly well-regarded for producing fresh, resonant messaging in a highly regulated space. The agency’s agility and responsiveness make it a favorite among startups and mid-market healthtech firms. Though its reporting tools leave room for improvement, the strategic clarity behind each campaign is hard to fault.
Location: London, UK
Year Established: 2015
Price Range: $$$
Average Review Score: 4.6/5
Services Offered: SEO, social media advertising, CRM optimization
Summary of Online Reviews |
Summary of Online Reviews: Reviews note their “creative campaign strategies”, value their “hands-on approach”; some say “reporting could be more robust”. |
Callbox

Callbox combines old-school hustle with modern CRM integration to deliver consistent appointment pipelines for healthcare B2B. Its global team is adept at navigating complex sales funnels, from hospitals to medtech vendors. While some clients have called for greater customization, many applaud the sheer volume and quality of interactions generated. For firms that value scale over nuance, Callbox remains a high-efficiency partner.
Location: Los Angeles, CA
Year Established: 2004
Price Range: $$$
Average Review Score: 4.4/5
Services Offered: B2B lead generation, appointment setting, account-based marketing
Summary of Online Reviews |
Summary of Online Reviews: Customers appreciate “consistent appointment delivery”, “good communication”; some wish for “more customization options”. |
Revnew

Revnew operates with a sales-first ethos that resonates with medical device and pharma firms looking to shorten their sales cycles. Its leads are often lauded for being high-intent and decision-maker level, a rarity in the space. Onboarding may take longer than expected, but the output is typically worth the wait. For revenue-focused marketing leaders, Revnew offers a hard-nosed, performance-oriented option.
Location: USA
Year Established: N/A
Price Range: $$
Average Review Score: 4.3/5
Services Offered: Healthcare lead generation, sales pipeline enhancement
Summary of Online Reviews |
Users like their “sales-driven focus”, find their leads “well-qualified”; some report “slow initial onboarding”. |
Launch Leads

Launch Leads offers a no-nonsense solution for healthcare businesses seeking more sales conversations without expanding internal teams. The agency is especially valuable for firms entering new markets or seeking to revitalize stagnant outreach. While its niche focus means fewer bells and whistles, Launch Leads earns praise for executional consistency and responsiveness. It’s an unflashy but reliable engine for sales productivity.
Location: USA
Year Established: N/A
Price Range: $$
Average Review Score: 4.1/5
Services Offered: Healthcare lead generation, appointment setting
Summary of Online Reviews |
Clients describe them as “reliable at securing appointments”, “responsive to feedback”; some feel they “could expand into more niches”. |
PointClear

PointClear is one of the more methodical players in the field, favoring quality touchpoints over high-volume outreach. Its structured, multi-touch programs appeal to enterprise-level healthcare organizations with long sales cycles. The agency’s senior team brings depth in compliance-heavy environments, a plus in regulated verticals. Although less aggressive in its approach, PointClear wins on rigor and conversion-ready prospects.
Location: Norcross, GA
Year Established: 1997
Price Range: $$
Average Review Score: 4.0/5
Services Offered: Prospect development, outsourced prospecting
Summary of Online Reviews |
Customers appreciate their “methodical approach”, find the team “professional and thorough”; some cite “longer sales cycles”. |
Zocdoc

Zocdoc operates at the intersection of healthcare access and digital convenience, with its booking platform becoming indispensable to many outpatient practices. It excels in high-volume lead delivery, particularly for consumer-facing providers in urban markets. The platform’s interface is user-friendly for both patients and providers, though the fee structure may challenge smaller clinics. Nonetheless, its category leadership and patient trust make it a default choice in digital health.
Location: New York, NY
Year Established: 2007
Price Range: $$$
Average Review Score: 4.5/5
Services Offered: Appointment scheduling, patient connection, practice management
Summary of Online Reviews |
Users call it “easy to use for patients”, appreciate the “increased appointment volume”; some feel “fees are high for smaller practices”. |